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Phrase(s): lose (all) one’s marbles
Go to lose one's marbles., Phrase(s): lose (all) one’s marbles [and] lose one’s mind
Fig. to go crazy; to go out of one’s mind. • What a silly thing to say! Have you lost your marbles? • Look at Sally jumping up and down and screaming. Is she losing all her marbles? • I can’t seem to remember anything. I think I’m losing my mind.
McGrawhill's American Idioms And Phrasal Verbs